Creutzfeldt-Jakob disease

Creutzfeldt-Jakob disease
rare (usually fatal) brain disease (usually in middle age) caused by an unidentified slow virus; characterized by progressive dementia and gradual loss of muscle control
Hypernyms: ↑brain disorder, ↑encephalopathy, ↑brain disease

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/kroyts"felt yah"kawp/, Pathol.
a rare, usually fatal brain disorder caused by an unidentified pathogen and characterized by progressive dementia, blindness, and involuntary movements.
Also, Creutzfeldt-Jacob disease. Also called Jakob-Creutzfeldt disease.
[1965-70; after German physicians Hans G. Creutzfeldt (1885-1964) and Alfons Jakob (1884-1931)]

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Creutzfeldt-Jakob disease /kroitsˈfelt yakˈob di-zēzˈ/
A degenerative condition of the brain thought to be caused by infection with a brain protein, called a prion, and characterized by diminishing muscle co-ordination, deterioration of the intellect and often blindness and loss of speech, one form of which (variant or new variant Creutzfeldt-Jakob disease) is thought to be associated with exposure to bovine spongiform encephalopathy from infected beef products (abbrev CJD)
ORIGIN: HG Creutzfeldt (1885–1964), and AM Jakob (1884–1931), German psychiatrists

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Creutzfeldt-Jakob disease UK [ˌkrɔɪtsfelt ˈjækɒb dɪˌziːz] US [ˌkrɔɪtsfelt ˈjɑkɔb dɪˌziz] noun [uncountable] medical
Thesaurus: specific diseaseshyponym general words for illnesses, diseases and medical conditionssynonym

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Creutzfeldt-Jakob disease [ˌkrɔɪtsfelt ˈjækɒb dɪziːz] [ˌkrɔɪtsfelt ˈjækɔːb dɪziːz] noun uncountable (abbr. CJD)
a brain disease that causes gradual loss of control of the mind and body and, finally, death. It is believed to be caused by ↑prions and is linked to ↑BSE in cows.
Word Origin:
[Creutzfeldt-Jakob disease] 1930s: named after H. G. Creutzfeldt (1885–1964) and A. Jakob (1882–1927), the German neurologists who first described cases of the disease in 1920–1. Creutzfeldt is credited with the first description of the disease in 1920, although the case is atypical by current diagnostic criteria; a year later Jakob described four cases, at least two of whom had clinical features suggestive of CJD as it is currently described.

Useful english dictionary. 2012.

Look at other dictionaries:

  • Creutzfeldt–Jakob disease — Classification and external resources Tonsil biopsy in variant CJD. Prion Protein immunostaining. ICD 10 A …   Wikipedia

  • Creutzfeldt-Jakob disease — ► NOUN ▪ a fatal degenerative disease affecting nerve cells in the brain. ● new variant Creutzfeldt Jakob disease Cf. ↑new variant Creutzfeldt Jakob disease ORIGIN named after the German neurologists H. G. Creutzfeldt and A. Jakob, who first… …   English terms dictionary

  • Creutzfeldt-Jakob disease — [kroits΄felt yä′kōb, kroits΄feld yä′kôp] n. an incurable degenerative disease of the nervous system thought to be caused by an unusual virus that incubates in the body for many years before symptoms appear …   English World dictionary

  • Creutzfeldt-Jakob disease — Infobox Disease Name = Creutzfeldt Jakob disease Caption = DiseasesDB = 3166 ICD10 = ICD10|A|81|0|a|80, ICD10|F|02|1|f|00 ICD9 = ICD9|046.1 ICDO = OMIM = 123400 MedlinePlus = eMedicineSubj = neuro eMedicineTopic = 725 MeshID = D007562 Creutzfeldt …   Wikipedia

  • Creutzfeldt-Jakob disease — /kroyts felt yah kawp/, Pathol. a rare, usually fatal brain disorder caused by an unidentified pathogen and characterized by progressive dementia, blindness, and involuntary movements. Also, Creutzfeldt Jacob disease. Also called Jakob… …   Universalium

  • Creutzfeldt-Jakob disease — Creutz·feldt Ja·kob disease also Creutz·feld Ja·kob disease .krȯits .felt .yä (.)kōb n a rare progressive fatal spongiform encephalopathy now usu. considered to be caused by a prion and marked by the development of porous brain tissue, premature …   Medical dictionary

  • Creutzfeldt-Jakob disease — CJD a rapidly progressive rare neurological disease, a form of human spongiform encephalopathy in which dementia progresses to death after a period of 3–12 months. There is no effective treatment. The causative agent is an abnormal prion protein… …   The new mediacal dictionary

  • Creutzfeldt–Jakob disease — [ˌkrɔɪtsfɛlt jakɒb] noun a fatal degenerative disease affecting nerve cells in the brain, believed to be caused by a prion. Phrases new variant Creutzfeldt–Jakob disease a form of the disease characterized by an early age of onset and possibly… …   English new terms dictionary

  • Creutzfeldt-Jakob disease — also Creutzfeld Jakob disease noun Etymology: Hans G. Creutzfeldt died 1964 German psychiatrist and Alfons M. Jakob died 1931 German psychiatrist Date: 1963 a rare progressive fatal encephalopathy caused by a prion and marked by development of… …   New Collegiate Dictionary

  • Creutzfeldt-Jakob disease — Creutz·feldt Ja·kob dis·ease || ‚krɔɪtsfelt jækÉ’b CJD, rare degenerative brain disease named after Hans G. Creutsfeldt and Alfons Jakob (disease is characterized by memory loss, jerky movements, stiff posture and seizures caused by a… …   English contemporary dictionary

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